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KMID : 0882420110810020266
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Korean Journal of Medicine
2011 Volume.81 No. 2 p.266 ~ p.272
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Two Cases of Cytomegalovirus Retinitis as a Manifestation of Good’s Syndrome
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Kim Hye-In
Chang Hyun-Ha
Park Ga-Young
Kwon Eu-Gene
Kim Hyo-Hoon
Kim Shin-Woo
Lee Jong-Myung
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Abstract
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Good’s syndrome (GS) is a rare cause of acquired combined B- and T-cell immunodeficiency in adults. GS is also known as a rare form of paraneoplastic syndrome of thymoma that may persist after thymectomy. Some reported GS cases have been related to various diseases as a result of humoral immunodeficiency, but no report to date has related GS to cytomegalovirus (CMV) retinitis in Korea. We report two cases of CMV retinitis as a manifestation of GS with severe cellular immunodeficiency. In the first case, a 61-year-old woman was diagnosed with GS manifesting as CMV retinitis combined with coincident pulmonary tuberculosis and soft-tissue tuberculosis. In the second case, a 56-year-old man had CMV retinitis and CMV pneumonia. Both patients had a history of thymoma and had received total thymectomies, and were diagnosed with GS a few years thereafter.
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KEYWORD
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Cytomegalovirus retinitis, Immunologic deficiency syndromes, Thymoma
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